From Theory to Practice: How Are Biological Reference Intervals Being Used?
According to the new version of ISO 15189:2022, biological reference intervals (RIs) and clinical decision limits shall be
defined, and their basis recorded, to reflect the patient population served by the laboratory, while considering the risk to patients. The importance of the RIs and clinical decision limits has also been addressed by the IFCC, and the Committee on Reference Intervals and Decision Limits (C-RIDL) has been established mostly for indirect methods for RI determination.
defined, and their basis recorded, to reflect the patient population served by the laboratory, while considering the risk to patients. The importance of the RIs and clinical decision limits has also been addressed by the IFCC, and the Committee on Reference Intervals and Decision Limits (C-RIDL) has been established mostly for indirect methods for RI determination.